ISSUE INFORMATION
REVIEW ARTICLE
Research progress and applications of optoelectronic synaptic devices based on 2D materials
- First Published: 20 October 2024

The inherent properties of two-dimensional (2D) materials make them ideal for use in artificial optoelectronic synaptic devices. This review explores synaptic devices based on 2D materials and examines their potential applications in image recognition, neuromorphic wearable electronic devices, logical operations and neuromorphic computing systems.
REVIEW ARTICLE
Mechanosensitive Piezo channels and their potential roles in peripheral auditory perception
- First Published: 20 October 2024
REVIEW ARTICLE
Brain perfusion alterations in patients and survivors of COVID-19 infection using arterial spin labeling: A systematic review
- First Published: 20 October 2024

Coronavirus disease (COVID-19) and long COVID can result in changes in brain perfusion, which may contribute to impaired cognition and hindered recovery. Arterial spin labeling (ASL), as a non-invasive magnetic resonance imaging technique, proves useful for investigating the effects of COVID-19 on cerebral function. This review emphasizes that both COVID-19 and long COVID may induce alterations in brain perfusion.
REVIEW ARTICLE
Microbiome-gut-brain axis as a novel hotspot in depression
- First Published: 19 October 2024

The microbiota-gut-brain axis serves as a critical link among the nervous, endocrine, and immune systems. In response to stress, cortisol levels are modulated by the hypothalamic-pituitary-adrenal (HPA) axis, which in turn influences immune cell activity and gut permeability. The intestinal microbiota engages with the brain through various pathways. The endocrine pathway affects the central nervous system via intestinal endocrine cells and microbial metabolites. Additionally, intestinal epithelial cells secrete immune cytokines and tryptophan metabolites that impact brain structure and function through the blood-brain barrier.
REVIEW ARTICLE
Promoting the welfare of animals utilized in neuroscience research
- First Published: 19 October 2024

This review addresses welfare issues through the 3Rs: refining experimental conditions, reducing animal usage, and replacing animals with alternative methods, and systematically examines the main kinds of model animals in neuroscience. Their current status is concisely summarized, representing a thoughtful and comprehensive consideration of the welfare aspects.
REVIEW ARTICLE
Posttranslational modifications in retinal degeneration diseases: An update on the molecular basis and treatment
- First Published: 15 October 2024
COMMENTARY
Reconstructing continuous language from brain signals measured by fMRI based brain-computer interface
- First Published: 08 October 2024
COMMENTARY
A novel neuronal circuit: Tanycytes mediate defensive metabolic responses following acute high-temperature exposure
- First Published: 08 October 2024

A schematic diagram of a proposed neural circuit for high temperature-induced feeding inhibition. Acute high temperature exposure activates excitatory neurons in the parabrachial nucleus brain area, promotes the release of vascular endothelial growth factor A from tanycytes, and acts on agouti-related protein neurons in the ARC brain area to inhibit feeding behavior.
REVIEW ARTICLE
A systematic review on investigating major depressive disorder and bipolar disorder using MRI and genetic data from 2018 to 2024
- First Published: 17 September 2024

This review examines genetic imaging studies on affective disorders (major depressive and bipolar disorder) published from 2018 to 2024. It summarizes the correlations between microscopic molecular features and macroscopic imaging characteristics and their impact on clinical manifestations, emphasizing the importance of epigenetic changes. Its findings will enhance our understanding of the pathogenesis of affective disorders.
REVIEW ARTICLE
Music therapy for depression: A narrative review
- First Published: 17 August 2024

This review summarizes and classifies the research in recent years and introduces the pathogenesis, diagnosis, and treatment methods of depression. The study of the principles of musical interventions for depression and the practice of musical interventions for depression with various etiologies are highlighted. It is hoped to introduce the progress of depression research and the prospect of music therapy.
COMMENTARY
Ultrasound-enabled delivery of drugs to the brain: Thinking outside the blood–brain barrier
- First Published: 16 August 2024
PERSPECTIVE
Peripheral sensory nerve regeneration: Novel target in bone tissue engineering
- First Published: 17 July 2024

This perspective paper introduces the importance of peripheral sensory nerve regeneration in bone healing, a cutting-edge direction in bone tissue engineering. By summarizing the latest knowledge in sensory nerve-bone interplay and the recent advances in biomaterial design for innervated bone tissue regeneration, this paper proposes critical guides for future bone engineering biomaterial design.
REVIEW ARTICLE
Advances of therapy for Alzheimer's disease: An updated review
- First Published: 15 July 2024

This article discusses the advancements in the treatment of Alzheimer's disease (AD) from both pharmacological and non-pharmacological perspectives. It elaborates on the advantages and disadvantages of each approach. In summary, the article documents five pharmaceutical treatment methods and five cutting-edge non-pharmacological treatment methods.
LETTER
A female patient with Alzheimer's disease via multimodality diagnostic approaches: A case report
- First Published: 14 July 2024